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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lg7h12orf4Zgc:154077. (581 aa)    
Predicted Functional Partners:
ppp1r21
Protein phosphatase 1, regulatory subunit 21.
    
 
 0.763
tbck
TBC1 domain containing kinase.
    
 
 0.709
LOC100708044
SLX1 homolog B, structure-specific endonuclease subunit.
   
    0.661
exoc8
Exocyst complex component 8.
   
    0.653
ENSONIP00000058603
annotation not available
    
 
 0.628
znf330
Zinc finger protein 330.
      
 0.569
tmem106c
Transmembrane protein 106C.
      
 0.568
zhx2
Zinc fingers and homeoboxes 2a.
    
 
 0.545
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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