sirt1 protein (Oreochromis niloticus) - STRING interaction network

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Score

sirt1

Deacetylase sirtuin-type domain-containing protein. (712 aa)

Predicted Functional Partners:

p53

0.999

ppargc1a

0.995

sirt7

0.988

LOC100706370

0.987

rps19bp1

0.986

sirt6

0.985

foxo3

0.984

nampt

0.983

pparg

0.977

rbp7

0.972

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100706370	foxo3	ENSONIP00000051243	ENSONIP00000016718	Fork-head domain-containing protein.	Forkhead box O3b.	0.916
LOC100706370	p53	ENSONIP00000051243	ENSONIP00000041809	Fork-head domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.851
LOC100706370	ppargc1a	ENSONIP00000051243	ENSONIP00000027136	Fork-head domain-containing protein.	PPARG coactivator 1 alpha.	0.761
LOC100706370	sirt1	ENSONIP00000051243	ENSONIP00000012918	Fork-head domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.987
LOC100706370	sirt6	ENSONIP00000051243	ENSONIP00000039918	Fork-head domain-containing protein.	Sirtuin 6.	0.582
LOC100706370	sirt7	ENSONIP00000051243	ENSONIP00000022389	Fork-head domain-containing protein.	Sirtuin 7.	0.405
foxo3	LOC100706370	ENSONIP00000016718	ENSONIP00000051243	Forkhead box O3b.	Fork-head domain-containing protein.	0.916
foxo3	p53	ENSONIP00000016718	ENSONIP00000041809	Forkhead box O3b.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.782
foxo3	ppargc1a	ENSONIP00000016718	ENSONIP00000027136	Forkhead box O3b.	PPARG coactivator 1 alpha.	0.761
foxo3	sirt1	ENSONIP00000016718	ENSONIP00000012918	Forkhead box O3b.	Deacetylase sirtuin-type domain-containing protein.	0.984
foxo3	sirt6	ENSONIP00000016718	ENSONIP00000039918	Forkhead box O3b.	Sirtuin 6.	0.582
foxo3	sirt7	ENSONIP00000016718	ENSONIP00000022389	Forkhead box O3b.	Sirtuin 7.	0.405
nampt	pparg	ENSONIP00000048300	ENSONIP00000018019	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	Peroxisome proliferator activated receptor gamma.	0.496
nampt	ppargc1a	ENSONIP00000048300	ENSONIP00000027136	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	PPARG coactivator 1 alpha.	0.480
nampt	rbp7	ENSONIP00000048300	ENSONIP00000002961	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	Nicotinamide-nucleotide adenylyltransferase.	0.973
nampt	sirt1	ENSONIP00000048300	ENSONIP00000012918	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	Deacetylase sirtuin-type domain-containing protein.	0.983
nampt	sirt6	ENSONIP00000048300	ENSONIP00000039918	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	Sirtuin 6.	0.956
nampt	sirt7	ENSONIP00000048300	ENSONIP00000022389	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	Sirtuin 7.	0.940
p53	LOC100706370	ENSONIP00000041809	ENSONIP00000051243	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Fork-head domain-containing protein.	0.851
p53	foxo3	ENSONIP00000041809	ENSONIP00000016718	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Forkhead box O3b.	0.782