Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100702127Nuclear receptor subfamily 1, group D, member 2b. (594 aa)    
Predicted Functional Partners:
I3JS28_ORENI
Nuclear receptor subfamily 1, group d, member 1.
   
 0.877
LOC100691220
Neuronal PAS domain protein 2.
    
 0.870
LOC100711812
Aryl hydrocarbon receptor nuclear translocator-like 2.
    
 0.827
ARNTL2
Aryl hydrocarbon receptor nuclear translocator like 2.
    
 0.827
LOC100703460
Clock circadian regulator b.
    
 0.824
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.805
LOC100694525
Cryptochrome circadian regulator 1a.
   
 0.800
ncor2
Nuclear receptor corepressor 2.
    
 0.775
ncor1
Nuclear receptor corepressor 1.
    
 0.775
arntl
Aryl hydrocarbon receptor nuclear translocator-like 1a.
    
 0.775
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.