Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100704015Rho guanine nucleotide exchange factor (GEF) 1a. (909 aa)    
Predicted Functional Partners:
I3K382_ORENI
Uncharacterized protein.
   
 0.934
cgnl1
Cingulin-like 1.
     
 0.896
cgn
Cingulin a.
     
 0.877
LOC100710602
Cingulin b.
     
 0.877
LOC109194537
Ribonuclease P/MRP 25 subunit-like.
    
   0.874
LOC100695471
Uncharacterized protein.
     
  0.866
nudcd1
NudC domain containing 1.
    
   0.760
LOC100694803
Ras homolog family member Cb.
   
 0.750
LOC100693083
Uncharacterized protein.
   
 0.750
LOC100710477
Ras homolog gene family, member Ab.
   
 0.750
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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