Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lhx1LIM homeobox 1a. (407 aa)    
Predicted Functional Partners:
ccnk
Cyclin K; Belongs to the cyclin family.
    
   0.762
wnt4
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
 0.686
I3IYF2_ORENI
LIM domain binding 2a.
    
 0.686
I3JSU9_ORENI
LIM domain binding 1a.
    
 0.686
LOC100706951
LIM-domain binding 1b.
    
 0.686
LOC100701954
Paired box 8.
   
 0.626
emx2
Empty spiracles homeobox 2.
     
 0.617
LOC100701233
Odd-skipped related transcription factor 1.
   
 0.611
pax2
Paired box 2b.
   
 0.609
LOC100698401
Homeobox B4a.
   
 0.570
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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