STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbx4T-box transcription factor 4. (546 aa)    
Predicted Functional Partners:
nkx2-5
NK2 homeobox 5.
   
 0.907
pitx1
Homeobox protein.
    
 
 0.775
yap1
Yes-associated protein 1.
    
 0.719
hoxb9
Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.
    
 
 0.717
hand2
Heart and neural crest derivatives expressed 2.
    
 0.677
LOC100690747
Tetraspanin.
      
 0.628
LOC100698401
Homeobox B4a.
    
 
 0.617
LOC100705260
Uncharacterized protein.
    
 0.610
LOC100700997
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
     
 0.599
kat2a
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
     
 0.599
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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