Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC100699837BSCL2 lipid droplet biogenesis associated, seipin. (421 aa)    
Predicted Functional Partners:
TMEM19
Transmembrane protein 19.
    
   0.762
use1
Unconventional SNARE in the ER 1 homolog (S. cerevisiae).
    
   0.756
Faxdc2
Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family.
    
 
 0.681
srxn1
Sulfiredoxin.
      
 0.600
blvrb
Biliverdin reductase B.
      
 0.521
LOC100534568
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.
      
 0.509
I3KW68_ORENI
Receptor expression-enhancing protein.
      
 0.497
tmem159
Uncharacterized protein.
      
 0.496
scarb1
Scavenger receptor class B, member 1; Belongs to the CD36 family.
   
  
 0.487
LOC100696033
Tetratricopeptide repeat domain 39B.
      
 0.483
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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