Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100695259Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (317 aa)    
Predicted Functional Partners:
wdr90
WD repeat domain 90.
    
 
 0.718
I3JR68_ORENI
NME/NM23 family member 8; Belongs to the NDK family.
    
 0.696
ENSONIP00000056453
annotation not available
   
 
 0.672
pacrg
PARK2 co-regulated.
    
 
 0.668
ENSONIP00000016918
Adenylate kinase 9.
    
 
 0.603
aspm
Abnormal spindle-like microcephaly-associated protein isoform X1.
      
 0.580
efhb
Uncharacterized protein.
   
   0.570
ccdc113
DUF4201 domain-containing protein.
   
 
 0.565
cfap44
Uncharacterized protein.
   
   0.564
zmynd12
Zinc finger, MYND-type containing 12.
    
   0.549
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (26%) [HD]