STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
angptl4Angiopoietin-like 4. (470 aa)    
Predicted Functional Partners:
atf2
Activating transcription factor 2.
      
 0.514
ENSONIP00000060288
MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1.
      
 0.482
LOC100706315
MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
      
 0.482
I3KLB2_ORENI
Uncharacterized protein.
      
 0.480
Vegfb
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
     
 0.466
dusp8
Dual specificity phosphatase 8a.
      
 0.461
pdgfc
Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family.
      
 0.454
LOC100709921
Insulin receptor substrate 4a.
    
 0.434
LOC102081223
Insulin receptor substrate 2-B.
    
 0.434
LOC100711438
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.431
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.