STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JWL8_ORENISHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (190 aa)    
Predicted Functional Partners:
mapkapk5
MAPK activated protein kinase 5.
    
 0.926
mapkapk2
MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily.
    
 0.926
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
    
 0.925
Mapkapk3
Mitogen-activated protein kinase-activated protein kinase 3.
    
 0.925
hspb1
SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.
     
  0.858
LOC100705966
Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family.
     
  0.858
LOC100705962
Chromodomain helicase DNA binding protein 4a.
      
 0.550
utp20
UTP20 small subunit processome component.
      
 0.547
ppia
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
      
 0.547
I3J4H0_ORENI
IST1 factor associated with ESCRT-III.
      
 0.547
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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