Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3JWN2_ORENIMetal response element binding transcription factor 2. (412 aa)    
Predicted Functional Partners:
eed
Embryonic ectoderm development.
   
 0.921
suz12
SUZ12 polycomb repressive complex 2 subunit b.
   
 0.868
LOC100701898
VEFS-Box domain-containing protein.
   
 0.868
ints1
Integrator complex subunit 1.
    
 0.863
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
   
 0.860
ezh2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
 0.860
Ints3
Integrator complex subunit 3.
    
 0.810
ints11
Integrator complex subunit 11.
   
 0.797
LOC100706337
WD_REPEATS_REGION domain-containing protein.
   
 0.779
LOC100711479
Retinoblastoma binding protein 4.
   
 0.779
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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