Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
spg11SPG11 vesicle trafficking associated, spatacsin. (2428 aa)    
Predicted Functional Partners:
Zfyve26
Zinc finger, FYVE domain containing 26.
   
 
 0.996
ap5z1
Adaptor related protein complex 5 subunit zeta 1.
    
 
 0.977
ap5m1
Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.
    
 
 0.967
ap5s1
Adaptor related protein complex 5 subunit sigma 1.
    
 
 0.941
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
      
 0.858
spg21
SPG21 abhydrolase domain containing, maspardin.
      
 0.764
I3KAX8_ORENI
Ataxin 2.
   
  
 0.756
synj1
Synaptojanin 1.
      
 0.754
atp13a2
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
      
 0.753
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
      
 0.753
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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