I3JWZ0_ORENI protein (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

I3JWZ0_ORENI

Protein kinase domain-containing protein. (473 aa)

Predicted Functional Partners:

pgam5

0.914

LOC100694194

0.884

Hsp90ab1

0.870

LOC100701982

0.870

chmp2a

0.865

vps4a

0.863

LOC100708589

0.860

chmp3

0.860

I3J330_ORENI

0.860

chmp7

0.859

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hsp90ab1	I3JWZ0_ORENI	ENSONIP00000032806	ENSONIP00000013385	Heat shock protein 90, alpha (cytosolic), class B member 1.	Protein kinase domain-containing protein.	0.870
Hsp90ab1	LOC100694194	ENSONIP00000032806	ENSONIP00000000393	Heat shock protein 90, alpha (cytosolic), class B member 1.	Receptor-interacting serine-threonine kinase 3.	0.925
Hsp90ab1	LOC100701982	ENSONIP00000032806	ENSONIP00000070041	Heat shock protein 90, alpha (cytosolic), class B member 1.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.916
I3J330_ORENI	I3JWZ0_ORENI	ENSONIP00000064098	ENSONIP00000013385	Transient receptor potential cation channel, subfamily M, member 7.	Protein kinase domain-containing protein.	0.860
I3JWZ0_ORENI	Hsp90ab1	ENSONIP00000013385	ENSONIP00000032806	Protein kinase domain-containing protein.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.870
I3JWZ0_ORENI	I3J330_ORENI	ENSONIP00000013385	ENSONIP00000064098	Protein kinase domain-containing protein.	Transient receptor potential cation channel, subfamily M, member 7.	0.860
I3JWZ0_ORENI	LOC100694194	ENSONIP00000013385	ENSONIP00000000393	Protein kinase domain-containing protein.	Receptor-interacting serine-threonine kinase 3.	0.884
I3JWZ0_ORENI	LOC100701982	ENSONIP00000013385	ENSONIP00000070041	Protein kinase domain-containing protein.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.870
I3JWZ0_ORENI	LOC100708589	ENSONIP00000013385	ENSONIP00000007587	Protein kinase domain-containing protein.	Charged multivesicular body protein 4C.	0.860
I3JWZ0_ORENI	chmp2a	ENSONIP00000013385	ENSONIP00000022922	Protein kinase domain-containing protein.	Charged multivesicular body protein 2A.	0.865
I3JWZ0_ORENI	chmp3	ENSONIP00000013385	ENSONIP00000025365	Protein kinase domain-containing protein.	Charged multivesicular body protein 3.	0.860
I3JWZ0_ORENI	chmp7	ENSONIP00000013385	ENSONIP00000013850	Protein kinase domain-containing protein.	Charged multivesicular body protein 7.	0.859
I3JWZ0_ORENI	pgam5	ENSONIP00000013385	ENSONIP00000065888	Protein kinase domain-containing protein.	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.	0.914
I3JWZ0_ORENI	vps4a	ENSONIP00000013385	ENSONIP00000069745	Protein kinase domain-containing protein.	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.	0.863
LOC100694194	Hsp90ab1	ENSONIP00000000393	ENSONIP00000032806	Receptor-interacting serine-threonine kinase 3.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.925
LOC100694194	I3JWZ0_ORENI	ENSONIP00000000393	ENSONIP00000013385	Receptor-interacting serine-threonine kinase 3.	Protein kinase domain-containing protein.	0.884
LOC100694194	LOC100701982	ENSONIP00000000393	ENSONIP00000070041	Receptor-interacting serine-threonine kinase 3.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.925
LOC100694194	pgam5	ENSONIP00000000393	ENSONIP00000065888	Receptor-interacting serine-threonine kinase 3.	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.	0.564
LOC100701982	Hsp90ab1	ENSONIP00000070041	ENSONIP00000032806	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.916
LOC100701982	I3JWZ0_ORENI	ENSONIP00000070041	ENSONIP00000013385	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Protein kinase domain-containing protein.	0.870