STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JWZ0_ORENIProtein kinase domain-containing protein. (473 aa)    
Predicted Functional Partners:
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.538
tradd
Tnfrsf1a-associated via death domain.
   
 0.531
LOC102081483
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.520
Fadd
Uncharacterized protein.
    
 0.508
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
0.484
ripk2
Receptor-interacting serine-threonine kinase 2.
    
0.476
ENSONIP00000000682
Intersectin 2a.
   
  0.462
I3KKD0_ORENI
Intersectin 2b.
   
  0.462
LOC100694194
Receptor-interacting serine-threonine kinase 3.
    
0.459
LOC109194160
Protein kinase domain-containing protein.
    
0.459
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.