Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSONIP00000013389annotation not available (310 aa)    
Predicted Functional Partners:
LOC100694194
Receptor-interacting serine-threonine kinase 3.
   
 0.978
LOC109194160
Protein kinase domain-containing protein.
   
 0.978
LOC100534578
Tumor necrosis factor b (TNF superfamily, member 2).
    
 0.945
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.921
pgam5
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.
    
 0.920
Hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
    
 0.881
LOC100701982
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
    
 0.881
I3J330_ORENI
Transient receptor potential cation channel, subfamily M, member 7.
     
 0.876
chmp2a
Charged multivesicular body protein 2A.
    
 0.873
vps4a
Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.
    
 0.871
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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