STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
herpud1Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1. (414 aa)    
Predicted Functional Partners:
atf4
Activating transcription factor 4a.
   
 
 0.524
LOC100703709
Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
      
 0.487
I3KZC4_ORENI
JunB proto-oncogene, AP-1 transcription factor subunit a.
      
 0.485
LOC100707881
JunB proto-oncogene, AP-1 transcription factor subunit b.
      
 0.483
Egr3
Early growth response 3.
      
 0.480
LOC100711598
V-fos FBJ murine osteosarcoma viral oncogene homolog Aa.
      
 0.480
I3JHR5_ORENI
MCL1 apoptosis regulator, BCL2 family member b.
      
 0.480
dusp5
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.473
Fosl2
Fos-like antigen 2.
      
 0.461
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
   
 
 0.461
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.