Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
herpud1Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1. (414 aa)    
Predicted Functional Partners:
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
   
 
 0.655
amfr
Autocrine motility factor receptor b.
   
 
 0.649
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
    
 
 0.553
atf4
Activating transcription factor 4a.
   
 
 0.530
edem1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
  
 0.496
LOC100706374
DnaJ heat shock protein family (Hsp40) member B9a.
   
  
 0.471
dnajb9
DnaJ heat shock protein family (Hsp40) member B9b.
   
  
 0.471
I3KZC4_ORENI
JunB proto-oncogene, AP-1 transcription factor subunit a.
   
  
 0.466
LOC100707881
JunB proto-oncogene, AP-1 transcription factor subunit b.
   
  
 0.465
psmg4
Proteasome assembly chaperone 4.
      
 0.462
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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