Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PITPNBPhosphatidylinositol transfer protein beta. (266 aa)    
Predicted Functional Partners:
pitpnm3
PITPNM family member 3.
 
    
 0.887
LOC100692781
Olfactomedin-like protein 2B isoform X2.
      
 0.588
LOC100694595
Multivesicular body subunit 12Bb.
      
 0.572
fbxl22
F-box and leucine-rich repeat protein 22.
      
 0.553
LOC100706053
Sp8 transcription factor b.
   
 0.479
med4
Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
 0.459
cog7
Component of oligomeric golgi complex 7.
   
 
 0.456
st13
ST13 Hsp70 interacting protein.
      
 0.452
dolk
Dolichol kinase.
    
 0.444
mtbp
MDM2 binding protein.
    
 
 0.419
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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