SDS protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SDS

Serine dehydratase. (329 aa)

Predicted Functional Partners:

LOC100693061

0.955

LOC100695998

0.944

cth

0.921

LOC100707770

0.917

mtr

0.899

LOC100695211

0.899

psph

0.898

LOC100707752

0.897

I3JKS7_ORENI

0.897

ENSONIP00000077375

0.897

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000077375	I3JKS7_ORENI	ENSONIP00000077375	ENSONIP00000009471	annotation not available	PALP domain-containing protein.	0.936
ENSONIP00000077375	LOC100693061	ENSONIP00000077375	ENSONIP00000019927	annotation not available	Threonine aldolase 1.	0.600
ENSONIP00000077375	LOC100695211	ENSONIP00000077375	ENSONIP00000074529	annotation not available	Zgc:172121; Involved in the regulation of homocysteine metabolism.	0.943
ENSONIP00000077375	LOC100695998	ENSONIP00000077375	ENSONIP00000062514	annotation not available	Serine--pyruvate aminotransferase.	0.930
ENSONIP00000077375	LOC100707752	ENSONIP00000077375	ENSONIP00000002371	annotation not available	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.916
ENSONIP00000077375	LOC100707770	ENSONIP00000077375	ENSONIP00000012399	annotation not available	Serine--pyruvate aminotransferase.	0.930
ENSONIP00000077375	SDS	ENSONIP00000077375	ENSONIP00000013420	annotation not available	Serine dehydratase.	0.897
ENSONIP00000077375	cth	ENSONIP00000077375	ENSONIP00000075088	annotation not available	Cystathionase (cystathionine gamma-lyase), like.	0.995
ENSONIP00000077375	mtr	ENSONIP00000077375	ENSONIP00000009098	annotation not available	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.958
ENSONIP00000077375	psph	ENSONIP00000077375	ENSONIP00000010225	annotation not available	Phosphoserine phosphatase.	0.942
I3JKS7_ORENI	ENSONIP00000077375	ENSONIP00000009471	ENSONIP00000077375	PALP domain-containing protein.	annotation not available	0.936
I3JKS7_ORENI	LOC100693061	ENSONIP00000009471	ENSONIP00000019927	PALP domain-containing protein.	Threonine aldolase 1.	0.974
I3JKS7_ORENI	LOC100695211	ENSONIP00000009471	ENSONIP00000074529	PALP domain-containing protein.	Zgc:172121; Involved in the regulation of homocysteine metabolism.	0.940
I3JKS7_ORENI	LOC100695998	ENSONIP00000009471	ENSONIP00000062514	PALP domain-containing protein.	Serine--pyruvate aminotransferase.	0.936
I3JKS7_ORENI	LOC100707752	ENSONIP00000009471	ENSONIP00000002371	PALP domain-containing protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.936
I3JKS7_ORENI	LOC100707770	ENSONIP00000009471	ENSONIP00000012399	PALP domain-containing protein.	Serine--pyruvate aminotransferase.	0.936
I3JKS7_ORENI	SDS	ENSONIP00000009471	ENSONIP00000013420	PALP domain-containing protein.	Serine dehydratase.	0.897
I3JKS7_ORENI	cth	ENSONIP00000009471	ENSONIP00000075088	PALP domain-containing protein.	Cystathionase (cystathionine gamma-lyase), like.	0.950
I3JKS7_ORENI	mtr	ENSONIP00000009471	ENSONIP00000009098	PALP domain-containing protein.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.937
I3JKS7_ORENI	psph	ENSONIP00000009471	ENSONIP00000010225	PALP domain-containing protein.	Phosphoserine phosphatase.	0.940