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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECTD4HECT domain E3 ubiquitin protein ligase 4. (4451 aa)    
Predicted Functional Partners:
evc
EvC ciliary complex subunit 1.
   
 0.698
LOC100692890
RAN binding protein 2.
   
 0.642
ND4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    
 
 0.580
gga3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3b.
   
 
 0.527
LOC100694605
Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.
   
 
 0.527
zfand4
Zinc finger, AN1-type domain 4.
    
 0.519
nup85
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
     
 0.516
LOC100702351
Diphthamide biosynthesis 3.
    
 
 0.504
adgrb3
Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family.
    
 0.489
adgrb1
Adhesion G protein-coupled receptor B1a; Belongs to the G-protein coupled receptor 2 family.
    
 0.489
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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