Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
HECTD4HECT domain E3 ubiquitin protein ligase 4. (4451 aa)    
Predicted Functional Partners:
evc
EvC ciliary complex subunit 1.
   
 0.923
brap
BRCA1 associated protein.
      
 0.917
LOC100692890
RAN binding protein 2.
   
 0.700
gga3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3b.
    
 
 0.697
LOC100694605
Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.
    
 
 0.697
LOC100698804
Si:ch1073-513e17.1.
    
 
 0.636
slc17a5
Solute carrier family 17 member 5.
    
 
 0.636
grasp
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein.
    
 
 0.631
ENSONIP00000026111
ADP-ribosylation factor 6b.
    
 0.560
nup85
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
     
 0.529
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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