Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PmpcaPeptidase (mitochondrial processing) alpha; Belongs to the peptidase M16 family. (563 aa)    
Predicted Functional Partners:
LOC100694607
Cytochrome c-1.
   
 0.989
I3J2W0_ORENI
Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family.
   
 0.972
LOC100705312
Ubiquinol-cytochrome c reductase core protein 1.
  
0.969
UQCRFS1
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 0.966
LOC100707594
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 0.966
pmpcb
Peptidase (mitochondrial processing) beta; Belongs to the peptidase M16 family.
   
 0.965
LOC100706772
Ubiquinol-cytochrome c reductase subunit 9.
   
 0.950
LOC100704109
Ubiquinol-cytochrome c reductase subunit 8.
   
 0.938
ndufv2
NADH:ubiquinone oxidoreductase core subunit V2.
   
 0.929
ndufs4
NADH:ubiquinone oxidoreductase subunit S4.
   
 0.927
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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