STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3K2B3_ORENIReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (505 aa)    
Predicted Functional Partners:
LOC100706145
Mothers against decapentaplegic homolog.
   
 0.961
smad1
Mothers against decapentaplegic homolog.
   
 0.956
bambi
BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.
    
 0.948
smad9
Mothers against decapentaplegic homolog.
   
 0.948
bmp6
Bone morphogenetic protein 6.
    
 0.946
LOC100709201
TGF_BETA_2 domain-containing protein.
   
 0.946
LOC100705058
Inhibin subunit beta B.
   
 0.946
bmp5
Bone morphogenetic protein 5.
    
 0.944
LOC100710325
Mothers against decapentaplegic homolog.
   
 0.943
SMAD3
Mothers against decapentaplegic homolog.
   
 0.943
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.