STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gsk3bGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (425 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.992
Frat2
Frequently rearranged in advanced T-cell lymphomas 2.
    
 0.989
LOC100695880
Uncharacterized protein.
   
 0.985
LOC100697931
Axin 1.
   
 0.985
AXIN2
Axin 2.
   
 0.983
LOC100698792
Axin 2 (conductin, axil).
   
 0.983
LOC100693960
Uncharacterized protein.
    
 0.977
LOC100700965
Dishevelled segment polarity protein 3a.
   
 0.954
dvl1
Dishevelled segment polarity protein 1a.
   
 0.954
I3KKZ9_ORENI
Uncharacterized protein.
   
 0.954
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.