STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100695148Epsin 3b. (597 aa)    
Predicted Functional Partners:
ENSONIP00000000682
Intersectin 2a.
    
 0.976
I3KKD0_ORENI
Intersectin 2b.
    
 0.976
eps15l1
Epidermal growth factor receptor pathway substrate 15-like 1a.
   
 0.957
LOC100694873
Epidermal growth factor receptor pathway substrate 15 like 1.
   
 0.957
LOC100708054
Epidermal growth factor receptor substrate 15 isoform X2.
   
 0.957
LOC102077612
Uncharacterized protein LOC102077612 isoform X1.
   
 0.925
gak
Cyclin G associated kinase.
   
 0.805
LOC100700052
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
 0.803
LOC100711613
Receptor protein-tyrosine kinase.
    
 0.797
egfr
Receptor protein-tyrosine kinase.
    
 0.793
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.