Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAC2Rac family small GTPase 2. (205 aa)    
Predicted Functional Partners:
nckap1l
NCK associated protein 1 like.
   
 0.962
pak2
Non-specific serine/threonine protein kinase.
   
 0.945
PAK2
Non-specific serine/threonine protein kinase.
   
 0.903
LOC100711936
BAI1 associated protein 2.
    
 0.903
LOC100696811
BAI1-associated protein 2a.
    
 0.903
BRK1
Chromosome 3 open reading frame 10.
   
 0.884
nckap1
NCK-associated protein 1.
   
 0.880
cyfip1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.879
LOC100705310
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.871
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
   
 0.870
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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