STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pkd1Polycystic kidney disease 1a. (4572 aa)    
Predicted Functional Partners:
pkd2
Polycystic kidney disease 2.
    
0.939
LOC100701261
Polycystic kidney disease 2-like 1.
    
0.939
Myot
Myotilin isoform X2.
    
 0.830
Exoc5
Exocyst complex component 5.
     
 0.667
nphp1
Nephrocystin-1 isoform X2.
   
 
 0.638
exoc4
Exocyst complex component 4.
     
 0.622
rtf2
Replication termination factor 2.
   
  
 0.619
tsc2
Rap-GAP domain-containing protein.
   
  
 0.616
trpc1
Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.594
exoc8
Exocyst complex component 8.
     
 0.590
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.