STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)    
Predicted Functional Partners:
chrd
Chordin; Belongs to the chordin family.
    
 
 0.786
LOC100694196
TGF_BETA_2 domain-containing protein.
   
 
 0.601
bmper
BMP binding endothelial regulator.
      
 0.589
bambi
BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.
      
 0.570
sall4
Spalt-like transcription factor 4.
      
 0.536
slc24a4
Solute carrier family 24 member 4b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.519
I3KWU7_ORENI
Nuclear receptor coactivator 3.
      
 0.490
NCOA3
Nuclear receptor coactivator.
      
 0.489
smoc1
SPARC related modular calcium binding 1.
      
 0.489
bmp2
Bone morphogenetic protein 2b.
   
 
 0.482
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.