STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (585 aa)    
Predicted Functional Partners:
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1.
   
 0.934
lig4
DNA ligase.
  
 0.851
I3KD07_ORENI
DNA ligase.
  
 0.847
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6.
    
 0.810
apex1
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
    
 0.795
pnkp
Polynucleotide kinase 3'-phosphatase.
    
 0.795
lig3
DNA ligase.
  
 0.783
rec114
REC114 meiotic recombination protein.
    
 0.777
xrcc5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
     
 0.775
LOC100702321
Probable flap endonuclease 1 homolog.
   
 0.749
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.