STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100711015Potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6. (373 aa)    
Predicted Functional Partners:
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.616
LOC100711397
Potassium inwardly-rectifying channel subfamily J member 16.
  
 
 
0.518
LOC100692811
Potassium inwardly-rectifying channel, subfamily J, member 16.
  
 
 
0.502
ENSONIP00000047729
annotation not available
   
  
 0.486
Abcc9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9.
 
  
 0.436
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8.
 
  
 0.436
KCNJ10
Potassium voltage-gated channel subfamily J member 10.
  
 
 
0.433
LOC100697257
Uncharacterized protein.
  
 
 
0.433
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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