STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nkx6-1NK6 homeobox 1. (320 aa)    
Predicted Functional Partners:
ENSONIP00000073744
Neurogenin 3.
   
  
 0.593
LOC100700859
Oligodendrocyte lineage transcription factor 2.
   
  
 0.571
nr5a2
Nuclear receptor subfamily 5, group A, member 2.
      
 0.571
ptf1a
Pancreas associated transcription factor 1a.
      
 0.567
neurod1
Neurogenic differentiation factor.
   
  
 0.497
LOC100704156
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.493
LOC100706552
Glucagon-1; Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level.
      
 0.491
pdx1
Pancreatic and duodenal homeobox 1.
   
0.456
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
  
 0.440
lhx4
LIM homeobox 4.
    
 
 0.421
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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