STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thTyrosine hydroxylase. (521 aa)    
Predicted Functional Partners:
LOC100702877
Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.
  
 0.795
PCBD2
Pterin-4 alpha-carbinolamine dehydratase 2.
  
 0.795
INSC
INSC spindle orientation adaptor protein.
      
 0.750
hgd
Homogentisate 1,2-dioxygenase.
  
  
 0.743
dbh
Dopamine beta-hydroxylase (dopamine beta-monooxygenase).
   
  
 0.660
dcx
Doublecortin.
      
 0.598
ENSONIP00000063313
Uncharacterized protein LOC106098379.
   
  
 0.592
comt
Catechol-O-methyltransferase b.
      
 0.578
LOC100691213
Uncharacterized protein; Belongs to the synuclein family.
    
 
 0.552
pgk1
Phosphoglycerate kinase.
      
 0.521
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.