STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsph9Radial spoke head 9 homolog. (277 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
   
 0.966
LOC100707731
Radial spoke head component 4A.
  
 
 0.962
rsph3
Radial spoke head 3.
  
 
 0.823
LOC100700052
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
 0.776
ap4e1
Adaptor related protein complex 4 subunit epsilon 1.
   
 0.767
LOC100694377
AP-1 complex subunit gamma.
   
 0.767
ap1g1
AP-1 complex subunit gamma.
   
 0.767
LOC100707472
AP complex subunit beta.
    
 0.759
ap1b1
AP complex subunit beta.
    
 0.759
ap4b1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.759
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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