STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100711264Mitogen-activated protein kinase kinase kinase 22. (618 aa)    
Predicted Functional Partners:
PAK2
Non-specific serine/threonine protein kinase.
    
0.936
pak2
Non-specific serine/threonine protein kinase.
    
0.936
MAP2K6
Mitogen-activated protein kinase kinase 6.
  
0.918
map3k3
Mitogen-activated protein kinase kinase kinase 3.
  
  
 
0.902
map3k2
Mitogen-activated protein kinase kinase kinase 2.
  
  
 
0.901
ccm2
CCM2 scaffold protein.
    
 0.826
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.803
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
  
0.777
LOC100711257
Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily.
   
0.698
map2k4
Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.
   
0.698
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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