STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spi1Spi-1 proto-oncogene b. (276 aa)    
Predicted Functional Partners:
myb
V-myb avian myeloblastosis viral oncogene homolog.
     
 0.811
ptprc
Protein tyrosine phosphatase receptor type C.
   
  
 0.767
csf3r
Colony stimulating factor 3 receptor (granulocyte).
   
 0.764
LOC100691239
Runt-related transcription factor.
   
 0.754
fli1
Fli-1 proto-oncogene, ETS transcription factor a.
   
 0.746
irf8
Interferon regulatory factor 8.
   
 
 0.744
LOC109194259
T-cell acute lymphocytic leukemia 1.
   
 
 0.711
ENSONIP00000035341
T-cell acute lymphocytic leukemia protein 1 homolog.
   
 
 0.711
LOC100703251
Interleukin-31 receptor subunit alpha.
   
 0.694
LOC100704899
Interferon regulatory factor.
   
 
 0.668
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.