STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nr1h4Nuclear receptor subfamily 1, group H, member 4. (488 aa)    
Predicted Functional Partners:
ppargc1a
PPARG coactivator 1 alpha.
   
 0.842
ncor2
Nuclear receptor corepressor 2.
    
 0.824
ncor1
Nuclear receptor corepressor 1.
    
 0.824
Rxra
Retinoid X receptor, alpha a.
   
0.820
I3J408_ORENI
Retinoid x receptor, beta b.
   
0.804
RXRB
Retinoid X receptor beta.
   
0.804
LOC100706800
Uncharacterized protein.
   
0.804
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.803
LOC100702791
Nuclear receptor subfamily 1, group D, member 2a.
   
0.801
LOC100702127
Nuclear receptor subfamily 1, group D, member 2b.
   
0.792
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.