STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3KJG6_ORENIRoundabout, axon guidance receptor, homolog 1 (Drosophila). (1694 aa)    
Predicted Functional Partners:
LOC100703331
Slit homolog 3 (Drosophila).
   
 0.817
I3JR60_ORENI
Slit homolog 2 (Drosophila).
   
 0.758
I3KPN0_ORENI
Slit homolog 1a (Drosophila).
   
 0.758
LOC100705354
Slit homolog 1b (Drosophila).
   
 0.758
nyx
Nyctalopin.
   
 0.745
med10
Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.624
sec24d
SEC24 homolog D, COPII coat complex component.
      
 0.614
Gtf2ird1
GTF2I repeat domain containing 1.
      
 0.597
cyfip1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
      
 0.589
baz1b
Bromodomain adjacent to zinc finger domain, 1B.
   
  
 0.585
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.