STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100704025ATP-binding cassette, sub-family C (CFTR/MRP), member 1. (1551 aa)    
Predicted Functional Partners:
LOC100700137
ATP-binding cassette, sub-family G (WHITE), member 2a.
   
 0.672
LOC100693338
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
  
 0.566
abcb11
ATP-binding cassette, sub-family B (MDR/TAP), member 11a.
   
0.519
I3J485_ORENI
Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.
   
  
 0.496
gopc
Golgi-associated PDZ and coiled-coil motif containing.
   
 0.493
HARBI1
Harbinger transposase derived 1.
      
 0.481
usp10
Ubiquitin carboxyl-terminal hydrolase.
    
  0.478
Prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
     
 0.460
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.452
kcnj5
Potassium inwardly-rectifying channel, subfamily J, member 5.
    
 0.430
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.