STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hrasHRas proto-oncogene, GTPase a. (189 aa)    
Predicted Functional Partners:
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
   
 0.980
Nf1
Neurofibromin 1b.
    
 0.976
I3JW49_ORENI
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.975
braf
B-Raf proto-oncogene serine/threonine-protein kinase.
   
 0.975
sos2
Son of sevenless homolog 2 (Drosophila).
   
 0.965
Sos1
Son of sevenless homolog 1 (Drosophila).
   
 0.965
rassf5
Ras association domain family member 5.
    
 0.957
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.950
LOC100707861
Zgc:158659; Belongs to the PI3/PI4-kinase family.
   
 0.950
LOC100704479
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.950
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.