STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
setd1a[histone H3]-lysine4 N-trimethyltransferase SETD1. (2262 aa)    
Predicted Functional Partners:
rbbp5
Retinoblastoma binding protein 5.
    
 0.979
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.979
LOC100705541
CXXC finger protein 1a.
   
 0.908
I3KWS1_ORENI
CXXC finger protein 1b.
   
 0.908
twf2
WD repeat domain 82.
   
 0.885
LOC100709494
Twinfilin actin-binding protein 2b.
   
 0.885
ENSONIP00000047919
Ubiquitin B.
   
 0.856
wdr5
WD repeat domain 5.
   
 0.852
wsb1
WD repeat and SOCS box containing 1.
   
 0.852
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.850
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.