STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ParlRhomboid domain-containing protein. (320 aa)    
Predicted Functional Partners:
stoml2
Stomatin (EPB72)-like 2.
   
 0.700
LOC100702835
YME1-like 1b.
   
 
 0.681
yme1l1
YME1-like 1a.
   
 
 0.681
pink1
PTEN induced kinase 1.
    
 
 0.626
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
   
 
 0.559
LOC100690566
Prohibitin.
   
 0.556
PHB2
Prohibitin.
   
 0.556
opa1
OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.524
Prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 
 0.522
pgam5
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.
   
  
 0.491
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.