STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1122 aa)    
Predicted Functional Partners:
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
   
 0.996
Pik3r6
Phosphoinositide-3-kinase regulatory subunit 6.
    
 0.986
LOC100690007
Phosphoinositide-3-kinase regulatory subunit 5.
   
 0.967
LOC102078679
Phosphoinositide-3-kinase, regulatory subunit 6b.
    
 0.948
LOC100706013
Inositol polyphosphate phosphatase-like 1b.
   
 
 0.919
inppl1
Inositol polyphosphate phosphatase-like 1a.
   
 
 0.919
LOC100706781
Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family.
  
  
 
0.904
Plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.855
LOC100702054
Guanine nucleotide binding protein (G protein), beta 5b.
    
 0.842
GNG5
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5.
     
  0.840
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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