STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vldlrVery low density lipoprotein receptor. (887 aa)    
Predicted Functional Partners:
pcsk9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
    
 0.840
RELN
Reelin.
    
 0.836
I3J3Q9_ORENI
DAB adaptor protein 1a.
    
 0.782
ldlrap1
Low density lipoprotein receptor adaptor protein 1b.
    
 0.750
LOC100693720
DAB adaptor protein 1b.
    
 0.726
ENSONIP00000000682
Intersectin 2a.
    
 0.645
dab2
DAB adaptor protein 2.
    
 0.645
I3KKD0_ORENI
Intersectin 2b.
    
 0.645
arhgap21
Rho GTPase activating protein 21a.
      
 0.640
LOC100698110
Dickkopf WNT signaling pathway inhibitor 1a.
    
 0.627
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.