STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100693794Rho guanine nucleotide exchange factor (GEF) 3, like. (522 aa)    
Predicted Functional Partners:
rrad
Ras-related associated with diabetes.
    
 0.733
I3J5Q5_ORENI
RAS protein activator like 3.
   
  
 0.708
LOC100699310
A kinase (PRKA) anchor protein 12b.
   
  
 0.684
ENSONIP00000000682
Intersectin 2a.
    
0.601
I3KKD0_ORENI
Intersectin 2b.
    
0.601
LOC100711529
Growth arrest specific 7.
   
 0.560
LOC100706459
Growth arrest-specific 7a.
   
 0.560
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.555
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.548
LOC100694803
Ras homolog family member Cb.
    
 0.521
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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