STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100704899Interferon regulatory factor. (319 aa)    
Predicted Functional Partners:
Mdm2
MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family.
    
  0.906
irf2
Interferon regulatory factor.
  
0.798
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.772
LOC100698988
E1A binding protein p300 a.
    
 0.738
LOC100700725
E1A binding protein p300 b.
    
 0.738
stat1
Signal transducer and activator of transcription.
   
 0.677
spi1
Spi-1 proto-oncogene b.
   
 
 0.668
I3KYD0_ORENI
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.646
LOC100699888
STIP1 homology and U-Box containing protein 1.
    
 
 0.641
LOC100709663
Interferon regulatory factor 10.
  
0.641
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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