STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spcs3Signal peptidase complex subunit 3. (181 aa)    
Predicted Functional Partners:
I3KKT2_ORENI
Signal peptidase complex subunit 2.
   
 0.989
ENSONIP00000067285
Signal peptidase complex subunit 1.
   
 0.986
sec11a
Signal peptidase complex catalytic subunit SEC11.
   
 0.970
grp
Uncharacterized protein.
   
 0.970
immp1l
Mitochondrial inner membrane protease subunit.
   
 0.852
immp2l
Mitochondrial inner membrane protease subunit 2 isoform X3.
   
 0.852
itfg2
Integrin alpha FG-GAP repeat containing 2.
   
 0.852
sec63
SEC63 homolog, protein translocation regulator.
    
 
 0.750
rpn2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
   
 0.680
srp19
Signal recognition particle 19.
   
  
 0.605
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.