STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3K1E4_ORENIGuanylate cyclase. (1134 aa)    
Predicted Functional Partners:
LOC100700851
Guanylate cyclase activator 1d.
    
 0.953
guca1b
Guanylate cyclase activator 1B.
   
 0.951
LOC100698069
Guanylate cyclase activator 1C.
   
 0.946
guca1a
Guanylate cyclase activator 1A.
   
 0.940
LOC100712122
Uncharacterized protein.
   
 0.909
nudt2
Nudix (nucleoside diphosphate linked moiety X)-type motif 2.
     
 0.905
LOC100697009
Guanylate cyclase activator 1g.
    
 0.903
LOC100708779
Guanylate cyclase.
  
  
 
0.902
itpa
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
    
  0.900
pde6g
Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.
   
 
 0.848
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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