STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSONIP00000061444annotation not available (444 aa)    
Predicted Functional Partners:
Fadd
Uncharacterized protein.
    
 0.892
LOC109194206
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
0.861
LOC100702139
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.861
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.829
I3KF49_ORENI
Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
 
 
0.801
LOC102083126
Uncharacterized protein.
   
 0.799
LOC100697530
Tumor necrosis factor receptor superfamily, member a.
    
 0.774
LOC100691526
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
 0.726
tradd
Tnfrsf1a-associated via death domain.
    
 0.699
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.689
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.