STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdia6Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family. (463 aa)    
Predicted Functional Partners:
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.977
Pdia4
Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.
   
0.972
p4hb
Protein disulfide-isomerase.
  
0.965
ero1a
Endoplasmic reticulum oxidoreductase alpha.
   
 0.965
gak
Cyclin G associated kinase.
    
 0.942
dnajb11
DnaJ heat shock protein family (Hsp40) member B11.
   
 
 0.908
LOC100709606
Peroxiredoxin 4.
  
 0.900
ddost
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
   
 
 0.887
LOC100701980
Calreticulin.
   
 0.874
LOC100711757
Calreticulin.
   
 0.874
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.