STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grb2Growth factor receptor-bound protein 2b. (222 aa)    
Predicted Functional Partners:
gab2
GRB2-associated binding protein 2.
    
 0.985
Sos1
Son of sevenless homolog 1 (Drosophila).
   
 0.984
LOC100707394
PH domain-containing protein.
    
 0.981
I3JUL5_ORENI
GRB2-associated binding protein 1.
    
 0.981
sos2
Son of sevenless homolog 2 (Drosophila).
   
 0.971
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
   
 0.962
LOC100693204
B cell linker.
    
 0.960
ptpra
Receptor-type tyrosine-protein phosphatase alpha.
   
 0.953
LOC100700918
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.944
ptpn11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.944
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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