STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSONIP00000065745Fasciclin-2-like. (251 aa)    
Predicted Functional Partners:
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.662
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.613
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.613
Birc6
Baculoviral IAP repeat containing 6.
   
 0.596
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.492
cenpn
Centromere protein N.
   
 0.466
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.441
cenpm
Proliferation associated nuclear element.
   
 0.435
LOC100711837
Uncharacterized protein.
   
 0.428
cenpk
Centromere protein K.
   
 0.423
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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