STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nr0b2Orphan nuclear receptor SHP. (258 aa)    
Predicted Functional Partners:
sf-1
SF-1/Ad4BP.
   
0.908
nr5a2
Nuclear receptor subfamily 5, group A, member 2.
   
0.908
LOC100690728
Hepatocyte nuclear factor 4, gamma.
   
0.722
hnf4a
Hepatocyte nuclear factor 4, alpha.
   
0.722
I3KDC7_ORENI
cAMP responsive element binding protein 3-like 3 like.
      
 0.687
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.683
LOC100699579
Nuclear receptor subfamily 1, group H, member 5.
   
 
 0.682
nr1h4
Nuclear receptor subfamily 1, group H, member 4.
   
 
 0.682
pparg
Peroxisome proliferator activated receptor gamma.
   
 0.681
PPARA
Peroxisome proliferator-activated receptor alpha b.
   
 0.680
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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