STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
synj1Synaptojanin 1. (1683 aa)    
Predicted Functional Partners:
inpp5b
Inositol polyphosphate-5-phosphatase B.
    
0.964
ocrl
OCRL inositol polyphosphate-5-phosphatase.
    
0.964
LOC100706013
Inositol polyphosphate phosphatase-like 1b.
    
0.952
inppl1
Inositol polyphosphate phosphatase-like 1a.
    
0.952
inpp5e
Inositol polyphosphate-5-phosphatase E.
    
0.951
ENSONIP00000000682
Intersectin 2a.
    
 
 0.948
I3KKD0_ORENI
Intersectin 2b.
    
 
 0.948
I3JAQ2_ORENI
SAC1 like phosphatidylinositide phosphatase a.
    
0.936
LOC100695712
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.922
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.922
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.